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Phys.org

Science & Environment / Phys.org

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New method swaps single atom in a molecule to speed drug discovery

Swapping out one letter in a word can entirely change its meaning. Similarly, swapping one atom in a molecule can completely change its identity. A group of chemists at the University of Chicago has demonstrated a new way to make a single-atom edit to a molecule without changing any of its other components. The innovative method can be used to make a family of molecules known as pyrroles, including many widely used medicines, and is significantly simpler, faster and more cost-effective than previous processes.

1 Sep 2026 2:10 am